2020-09-01
Small
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ConnectType:
T - Technology & Patents
Industry:
Fine Chemical ManufacturingNew Materials and Polymer MaterialsPharmaceuticals and Chemical Intermediates
Country / Region:
China
Company Type:
State-controlled enterprise
Registered Capital:
5 million RMB
Company Capability: Process Technology Development、Technology Transfer、Chemical Technology & Patents
Shanxi Synthetic Biology Institute Co., Ltd. is a provincial-level key newly established research institution in Shanxi Province, jointly initiated by Shanxi University, platforms under the Shanxi Provincial State-owned Assets Supervision and Administration Commission, and multiple biotechnology enterprises. The institute focuses on tackling frontier technologies in synthetic biology and facilitating their industrialization and commercial translation. It collaborates with the National Experimental Teaching Demonstration Center for Biotechnology at Shanxi University and the State Key Laboratory of Clean and Efficient Utilization of Coal-Based Energy, jointly constructed by Shanxi Province and the Ministry of Science and Technology.
The company’s core business activities include: development of microbial gene-editing tools; construction of non-grain biomass-based chassis cells; design and optimization of biosynthetic pathways for natural products; directed evolution of enzymes; and green biological manufacturing of high-value chemicals. Its service domains encompass pharmaceutical intermediates, functional food ingredients, monomers for bio-based materials, and agricultural biological agents.
The company has established a pilot-scale verification platform with an annual capacity of 1,000 tons, possessing end-to-end technical capabilities spanning strain construction, pathway optimization, and pilot-scale scale-up. Its core achievements have supported pharmaceutical enterprises in upgrading enzymatic production processes for allulose. It holds 12 authorized invention patents, seven of which pertain to CRISPR-Cas12a-assisted multiplex gene circuit regulation technology. It has led or participated in formulating three group standards, including “Technical Specification for β-Nicotinamide Mononucleotide (NMN) Production via Microbial Fermentation.”
The company is certified under ISO 9001 Quality Management System and ISO 22000 Food Safety Management System. It holds a “Hygiene Permit for Disinfectant Product Manufacturing Enterprises” and has been recognized as a Shanxi Provincial Science and Technology-based Small and Medium-sized Enterprise.
Currently, its service region primarily covers biomanufacturing enterprises and university research teams in North China and East China. Collaborating institutions include the Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, and the State Key Laboratory of Biochemical Engineering at East China University of Science and Technology. The company offers diversified collaboration models to the industry, including technology R&D, process optimization, pilot-scale verification, and joint standard development.
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